Gene Wilder, who established himself as one of America’s foremost comic actors with his delightfully neurotic performances in three films directed by Mel Brooks; his eccentric star turn in the family classic “Willy Wonka and the Chocolate Factory”; and his winning chemistry with Richard Pryor in the box-office smash “Stir Crazy,” died early  at his home in Stamford, Conn. He was 83.

Mr. Wilder was an accomplished stage actor as well as a screenwriter, a novelist and the director of four movies in which he starred. But he was best known for playing roles on the big screen that might have been ripped from the pages of the Diagnostic and Statistical Manual of Mental Disorders.

He made his movie debut in 1967 in Arthur Penn’s celebrated crime drama, “Bonnie and Clyde,” in which he was memorably hysterical as an undertaker kidnapped by the notorious Depression-era bank robbers played by Faye Dunaway and Warren Beatty. He was even more hysterical, and even more memorable, a year later in “The Producers,” the first film by Mr. Brooks, who later turned it into a Broadway hit.

He was nominated for a Golden Globe for his performance as the wizardly title character in “Willy Wonka and the Chocolate Factory” (1971).